Return to the Cognitive Enhancement Research Institute Home Page or Special Menus Page.

The Down’s Syndrome Page

The following two articles are reproduced here in their entirity, complete with graphics, charts, sidebars and scientific references.

Smart Drugs and Down’s Syndrome: This is the first article we ever published about the application of smart drugs to Down’s syndrome. Written by Steven Wm. Fowkes and Dr. Ward Dean and published on Valentine’s Day in February 1994, it covered the history and modern uses of nutritional therapy for trisomy 21, which would later become described as targetted nutritional intervention (TNI). Starting with the pioneering work of Dr. Henry Turkel and leading up to the latest contributions of Dixie Lawrence, this article lays a foundation for the articles to follow. It is reproduced here in its entirity.

An Interview with Dixie Lawrence: This full-length interview with Dixie Lawrence detailed many of the approaches Dixie pioneered with her daughter and provides many practical tips for the successful implementation of nutritional therapy and piracetam in children. It is reproduced here in its entirity.

The following three articles are presented only in part. Introductory paragraphs are presented in full-text, and the rest of the articles are summarized. References are omitted.

Antioxidant Intervention in Down’s Syndrome: This article and the following article were published two years after the first article. These articles were written partly to provide information to parents and partly to provide information to doctors. This article focusses on the problem of oxidative stress in Down’s syndrome and has several sidebars which illustrate free radicals and oxidation-reduction reactions (redox chemistry).

Nutritional Intervention in Down’s Syndrome: This article focusses on nutrition issues surrounding collagen (connective tissue) metabolism, methylation metabolism, ammonia metabolism and mineral deficiencies.

The Case for Piracetam in Down’s Syndrome: This latest feature article is on the use of piracetam in Down’s syndrome and other related conditions. It summarizes old research dealing with piracetam and Down’s syndrome and then covers recent major research findings for conditions that may be related to this use (i.e., piracetam use in children with sickle-cell anemia and Angelman syndrome, heart disease, hypoxia and anoxia, ataxia, apraxia, etc. This article contains over two dozen references to recent literature, review articles on piracetam, and drug reference guides (European equivalents to the US Physician’s Desk Reference or PDR).

Additional discussions of Down’s syndrome have taken place in the Question & Answer section of Smart Drug News. Some of these discussions can be found in the back issues descriptions and others in our question-and-answer page on site.

2001 Update:

CERI’s brand new Down’s Syndrome Collection is now available for sale at the Smart Life News Online Store. This publication is a complete compilation of every page in every newsletter that has content relating to Down’s syndrome. It contains:

All five full-length feature articles described above,
—complete with graphics, illustrations and scientific references,

All nine sidebars dealing with free radicals, oxidative stress during surgery,
Dr. Lee-Benner’s visit to the Warner House, glutathione, the SAM cycle,
the Fiona study, piracetam, and much more, and

All 28 Q&A's covering a wide spectrum of Down’s syndrome-related topics,

That’s 44 information-packed items, extracted from 26 newsletters, comprising 87 pages, all in one downloadable publication, for less than $25. This kind of specialized publication at this low price is only possible due to the technological capabilities of the Internet. (Purchased as separate newsletters, it would cost over $75!) And it is delivered right to your computer, no shipping charges, no postal delays, as fast as your modem can download it. You can then read it on your computer monitor, or print out hard copies of any or all pages — or both — at your preference. Don’t wait. Go to the Online Store and get the Down’s Syndrome Collection today.

To go to the Smart Life News Online Store, click here.

Individual back issues and bundles of back issues can also be ordered at the Online Store. These can be ordered as downloads, or as printed-on-paper back issues delivered by mail.

Information on ordering hard copies of these articles and issues, or other related issues, can be accessed from the home page or the order information page. To keep current with ongoing developments in these areas, subscribe to Smart Life News. Subscriptions start at $35 and not only include the Resources Listing, but direct access to CERI Executive Director Steven Fowkes on Tuesday afternoons for personal answers to subscriber’s questions.